Review Article

Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review

Table 4

Applications of PLGA microparticles in dentistry.

FieldPLGA microparticlesLoaded withStudy

Endodontic therapyPLGA microparticles
with added zein
Amoxicillin[80]
Dental caries vaccinationPLGA microparticles
coated with chitosan
Recombinant Streptococcusmutans glucan-binding protein D[81]
Dental regeneration
(tertiary dentin)
PLGA microparticles
in a PLGA/calcium phosphate cement
Growth factors[14]
Haemostatic devicePLGA microparticlesThrombin[85]
periodontal treatment PLGAmicroparticles Hydroxyapatite
ofloxacine
[88]
PLGA microparticlesChlorhexidine[87]
PDLLA-PLGA microparticlesGrowth and differentiation factors [89]
PLGA and poly(epsilon-caprolactone)Doxycycline[84]
Bone regenerationPLGA microparticlesSimvastatin[91]
PLGA microparticlesAlendronate sodium [97]

Implant therapyPLGA microparticles Dexamethasone[94]
PLGA microparticles in collagen membraneDexamethasone[93]
PLGA microparticles in
PLGA membrane
VEGF (vascular endothelial growth factor)[92]
PLGA microparticlesInsulin[82, 83]
PLGA microparticlesBasic fibroblast factor[96]
PLGA microparticlesFluvastatin [98]
PLGA microparticlesrhBMp-2 (recombinant human bone morphogenetic protein-2)[99]