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Journal of Chemistry
Volume 2015, Article ID 613268, 10 pages
http://dx.doi.org/10.1155/2015/613268
Research Article

Mango Fruit Extracts Differentially Affect Proliferation and Intracellular Calcium Signalling in MCF-7 Human Breast Cancer Cells

1School of Pharmacy, The University of Queensland, Brisbane, QLD 4072, Australia
2Queensland Alliance for Agriculture and Food Innovation, Centre for Nutrition and Food Sciences, The University of Queensland, Brisbane, QLD 4072, Australia

Received 1 December 2014; Accepted 7 January 2015

Academic Editor: Artur M. S. Silva

Copyright © 2015 Meng-Wong Taing et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. K. Lin, “Cancer chemoprevention by tea polyphenols through modulating signal transduction pathways,” Archives of Pharmacal Research, vol. 25, no. 5, pp. 561–571, 2002. View at Publisher · View at Google Scholar · View at Scopus
  2. S. C. Thomasset, D. P. Berry, G. Garcea, T. Marczylo, W. P. Steward, and A. J. Gescher, “Dietary polyphenolic phytochemicals—promising cancer chemopreventive agents in humans? A review of their clinical properties,” International Journal of Cancer, vol. 120, no. 3, pp. 451–458, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. J. T. Pierson, R. G. Dietzgen, P. N. Shaw, S. J. Roberts-Thomson, G. R. Monteith, and M. J. Gidley, “Major Australian tropical fruits biodiversity: bioactive compounds and their bioactivities,” Molecular Nutrition and Food Research, vol. 56, no. 3, pp. 357–387, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. R. E. Litz, The Mango: Botany, Production and Uses, CAB International, Cambridge, Mass, USA, 2nd edition, 2009.
  5. M. W. Taing, J. T. Pierson, P. N. Shaw et al., “Mango (Mangifera indica L.) peel extract fractions from different cultivars differentially affect lipid accumulation in 3T3-L1 adipocyte cells,” Food and Function, vol. 4, no. 3, pp. 481–491, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. G. D. Noratto, M. C. Bertoldi, K. Krenek, S. T. Talcott, P. C. Stringheta, and S. U. Mertens-Talcott, “Anticarcinogenic effects of polyphenolics from mango (Mangifera indica) varieties,” Journal of Agricultural and Food Chemistry, vol. 58, no. 7, pp. 4104–4112, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. M. W. Taing, J. T. Pierson, V. L. T. Hoang et al., “Mango fruit peel and flesh extracts affect adipogenesis in 3T3-L1 cells,” Food and Function, vol. 3, no. 8, pp. 828–836, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. N. Khan, F. Afaq, and H. Mukhtar, “Cancer chemoprevention through dietary antioxidants: progress and promise,” Antioxidants and Redox Signaling, vol. 10, no. 3, pp. 475–510, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. G. L. Russo, “Ins and outs of dietary phytochemicals in cancer chemoprevention,” Biochemical Pharmacology, vol. 74, no. 4, pp. 533–544, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. L. S. Adams, S. Phung, N. Yee, N. P. Seeram, L. Li, and S. Chen, “Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway,” Cancer Research, vol. 70, no. 9, pp. 3594–3605, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. P. García-Solís, E. M. Yahia, V. Morales-Tlalpan, and M. Díaz-Muñoz, “Screening of antiproliferative effect of aqueous extracts of plant foods consumed in México on the breast cancer cell line MCF-7,” International Journal of Food Sciences and Nutrition, vol. 60, no. 6, pp. 32–46, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. Y.-J. Surh, “Cancer chemoprevention with dietary phytochemicals,” Nature Reviews Cancer, vol. 3, no. 10, pp. 768–780, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. D. Boivin, S. Lamy, S. Lord-Dufour et al., “Antiproliferative and antioxidant activities of common vegetables: a comparative study,” Food Chemistry, vol. 112, no. 2, pp. 374–380, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. J. M. Schmitt, E. Abell, A. Wagner, and M. A. Davare, “ERK activation and cell growth require CaM kinases in MCF-7 breast cancer cells,” Molecular and Cellular Biochemistry, vol. 335, no. 1-2, pp. 155–171, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. C. C. Chen, W.-R. Lee, and S. Safe, “Egr-1 is activated by 17beta-estradiol in MCF-7 cells by mitogen-activated protein kinase-dependent phosphorylation of ELK-1,” Journal of Cellular Biochemistry, vol. 93, no. 5, pp. 1063–1074, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Improta-Brears, A. R. Whorton, F. Codazzi, J. D. York, T. Meyer, and D. P. Mcdonnel, “Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium,” Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 8, pp. 4686–4691, 1999. View at Publisher · View at Google Scholar · View at Scopus
  17. J. H. Gutzman, S. E. Nikolai, D. E. Rugowski, J. J. Watters, and L. A. Schuler, “Prolactin and estrogen enhance the activity of activating protein 1 in breast cancer cells: role of extracellularly regulated kinase 1/2-mediated signals to c-fos,” Molecular Endocrinology, vol. 19, no. 7, pp. 1765–1778, 2005. View at Publisher · View at Google Scholar · View at Scopus
  18. K. Dampier, E. A. Hudson, L. M. Howells, M. M. Manson, R. A. Walker, and A. Gescher, “Differences between human breast cell lines in susceptibility towards growth inhibition by genistein,” British Journal of Cancer, vol. 85, no. 4, pp. 618–624, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. G. R. Monteith, D. McAndrew, H. M. Faddy, and S. J. Roberts-Thomson, “Calcium and cancer: targeting Ca2+ transport,” Nature Reviews Cancer, vol. 7, no. 7, pp. 519–530, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. D. P. Drew, N. Krichau, K. Reichwald, and H. T. Simonsen, “Guaianolides in apiaceae: perspectives on pharmacology and biosynthesis,” Phytochemistry Reviews, vol. 8, no. 3, pp. 581–599, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Kuttan, P. Bhanumathy, K. Nirmala, and M. C. George, “Potential anticancer activity of turmeric (Curcuma longa),” Cancer Letters, vol. 29, no. 2, pp. 197–202, 1985. View at Publisher · View at Google Scholar · View at Scopus
  22. S. M. Wilkinson and M. H. Beck, “Allergic contact dermatitis from menthol in peppermint,” Contact Dermatitis, vol. 30, no. 1, pp. 42–43, 1994. View at Publisher · View at Google Scholar · View at Scopus
  23. A. M. Bode and Z. Dong, “The two faces of capsaicin,” Cancer Research, vol. 71, no. 8, pp. 2809–2814, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. N. L. Dillon, I. S. E. Bally, C. L. Wright, L. Hucks, D. J. Innes, and R. G. Dietzgen, “Genetic diversity of the Australian National Mango Genebank,” Scientia Horticulturae, vol. 150, pp. 213–226, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. R. J. Schnell, J. S. Brown, C. T. Olano, A. W. Meerow, R. J. Campbell, and D. N. Kuhn, “Mango genetic diversity analysis and pedigree inferences for Florida cultivars using microsatellite markers,” Journal of the American Society for Horticultural Science, vol. 131, no. 2, pp. 214–224, 2006. View at Google Scholar · View at Scopus
  26. A. U. Malik and Z. Singh, “Pre-storage application of polyamines improves shelf-life and fruit quality of mango,” Journal of Horticultural Science & Biotechnology, vol. 80, no. 3, pp. 363–369, 2005. View at Google Scholar · View at Scopus
  27. N. H. Daud, C. S. Aung, A. K. Hewavitharana et al., “Mango extracts and the mango component mangiferin promote endothelial cell migration,” Journal of Agricultural and Food Chemistry, vol. 58, no. 8, pp. 5181–5186, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. C. J. Goodwin, S. J. Holt, S. Downes, and N. J. Marshall, “Microculture tetrazolium assays: a comparison between two new tetrazolium salts, XTT and MTS,” Journal of Immunological Methods, vol. 179, no. 1, pp. 95–103, 1995. View at Publisher · View at Google Scholar · View at Scopus
  29. D. McAndrew, D. M. Grice, A. A. Peters et al., “ORAI1-mediated calcium influx in lactation and in breast cancer,” Molecular Cancer Therapeutics, vol. 10, no. 3, pp. 448–460, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. W. J. Lee, G. R. Monteith, and S. J. Roberts-Thomson, “Calcium transport and signaling in the mammary gland: targets for breast cancer,” Biochimica et Biophysica Acta, vol. 1765, no. 2, pp. 235–255, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. D. M. Grice, I. Vetter, H. M. Faddy, P. A. Kenny, S. J. Roberts-Thomson, and G. R. Monteith, “Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of Insulin-like Growth Factor Receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231,” Journal of Biological Chemistry, vol. 285, no. 48, pp. 37458–37466, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. J. T. Pierson, G. R. Monteith, S. J. Roberts-Thomson, R. G. Dietzgen, M. J. Gidley, and P. N. Shaw, “Phytochemical extraction, characterisation and comparative distribution across four mango (Mangifera indica L.) fruit varieties,” Food Chemistry, vol. 149, pp. 253–263, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. M. Masibo and H. Qian, “Major mango polyphenols and their potential significance to human health,” Comprehensive Reviews in Food Science and Food Safety, vol. 7, no. 4, pp. 309–319, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. S. M. R. Ribeiro, L. C. A. Barbosa, J. H. Queiroz, M. Knödler, and A. Schieber, “Phenolic compounds and antioxidant capacity of Brazilian mango (Mangifera indica L.) varieties,” Food Chemistry, vol. 110, no. 3, pp. 620–626, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. Y. F. Chu, J. Sun, X. Wu, and R. H. Liu, “Antioxidant and antiproliferative activities of common vegetables,” Journal of Agricultural and Food Chemistry, vol. 50, no. 23, pp. 6910–6916, 2002. View at Publisher · View at Google Scholar · View at Scopus
  36. S. S. Percival, S. T. Talcott, S. T. Chin, A. C. Mallak, A. Lounds-Singleton, and J. Pettit-Moore, “Neoplastic transformation of BALB/3T3 cells and cell cycle of HL-60 cells are inhibited by mango (Mangifera indica L.) juice and mango juice extracts,” Journal of Nutrition, vol. 136, no. 5, pp. 1300–1304, 2006. View at Google Scholar · View at Scopus
  37. J. Sun, Y.-F. Chu, X. Wu, and R. H. Liu, “Antioxidant and antiproliferative activities of common fruits,” Journal of Agricultural and Food Chemistry, vol. 50, no. 25, pp. 7449–7454, 2002. View at Publisher · View at Google Scholar · View at Scopus
  38. E. B. Izevbigie, J. L. Bryant, and A. Walker, “A novel natural inhibitor of extracellular signal-regulated kinases and human breast cancer cell growth,” Experimental Biology and Medicine, vol. 229, no. 2, pp. 163–169, 2004. View at Google Scholar · View at Scopus
  39. N. Atanaskova, V. G. Keshamouni, J. S. Krueger, J. A. Schwartz, F. Miller, and K. B. Reddy, “MAP kinase/estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance,” Oncogene, vol. 21, no. 25, pp. 4000–4008, 2002. View at Publisher · View at Google Scholar · View at Scopus
  40. A. Adeyinka, Y. Nui, T. Cherlet, L. Snell, P. H. Watson, and L. C. Murphy, “Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression,” Clinical Cancer Research, vol. 8, no. 6, pp. 1747–1753, 2002. View at Google Scholar · View at Scopus
  41. K. M. Witherup, R. W. Ransom, A. C. Graham et al., “Martinelline and martinellic acid, novel G-protein linked receptor antagonists from the tropical plant Martinella iquitosensis (Bignoniaceae),” Journal of the American Chemical Society, vol. 117, no. 25, pp. 6682–6685, 1995. View at Publisher · View at Google Scholar · View at Scopus
  42. Y. Albert Yen, M. Herenyiova, and G. Weber, “Quercetin: synergistic action with carboxyamidotriazole in human breast carcinoma cells,” Life Sciences, vol. 57, no. 13, pp. 1285–1292, 1995. View at Publisher · View at Google Scholar · View at Scopus
  43. Y. Guo, Y. J. Hong, H.-J. Jang et al., “Octyl gallate inhibits ATP-induced intracellular calcium increase in PC12 cells by inhibiting multiple pathways,” Korean Journal of Physiology and Pharmacology, vol. 14, no. 1, pp. 21–28, 2010. View at Publisher · View at Google Scholar · View at Scopus
  44. A. O. da Conceição, L. Takser, and J. Lafond, “Effect of St. John's wort standardized extract and hypericin on in vitro placental calcium transport,” Journal of Medicinal Food, vol. 13, no. 4, pp. 934–942, 2010. View at Publisher · View at Google Scholar · View at Scopus
  45. Y. A. Mahmmoud, “Modulation of protein kinase C by curcumin; inhibition and activation switched by calcium ions,” British Journal of Pharmacology, vol. 150, no. 2, pp. 200–208, 2007. View at Publisher · View at Google Scholar · View at Scopus
  46. N. Sakaguchi, M. Inoue, and Y. Ogihara, “Reactive oxygen species and intracellular Ca2, common signals for apoptosis induced by gallic acid,” Biochemical Pharmacology, vol. 55, no. 12, pp. 1973–1981, 1998. View at Publisher · View at Google Scholar · View at Scopus
  47. W. Thomas, N. Coen, S. Faherty, C. Ó. Flatharta, and B. J. Harvey, “Estrogen induces phospholipase A2 activation through ERK1/2 to mobilize intracellular calcium in MCF-7 cells,” Steroids, vol. 71, no. 3, pp. 256–265, 2006. View at Publisher · View at Google Scholar · View at Scopus
  48. C. Szatkowski, J. B. Parys, H. Ouadid-Ahidouch, and F. Matifat, “Inositol 1,4,5-trisphosphate-induced Ca2+ signalling is involved in estradiol-induced breast cancer epithelial cell growth,” Molecular Cancer, vol. 9, article 156, 2010. View at Publisher · View at Google Scholar · View at Scopus