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Journal of Chemistry
Volume 2015 (2015), Article ID 629085, 22 pages
Review Article

Bioactive Phytochemicals: Bioactivity, Sources, Preparations, and/or Modifications via Silver Tetrafluoroborate Mediation

Department of Agriculture, Central University of Technology, Free State, 1 Park Road, Bloemfontein 9300, South Africa

Received 12 August 2014; Accepted 5 March 2015

Academic Editor: Patricia Valentao

Copyright © 2015 Matthew C. Achilonu and Dennis O. Umesiobi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This review provides an overview of the biological activities, natural occurrences, and the silver tetrafluoroborate- (AgBF4-) mediated synthesis of proanthocyanidins, glycosides, N-heterocyclic alkaloid analogues (of pyrrole, morphine, quinoline, isoquinoline, and indole), furan analogues, and halocompounds. AgBF4 has been reviewed as an effective reaction promoter, used extensively in the synthesis of relevant biologically active compounds via carbon-carbon and carbon-heteroatom bonds formation. The literatures from 1979 to April 2014 were reviewed.