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Journal of Chemistry
Volume 2015, Article ID 630408, 7 pages
http://dx.doi.org/10.1155/2015/630408
Research Article

Conductive Composite Biosensor System for Electrochemical Indinavir Drug Detection

SensorLab, Department of Chemistry, University of Western Cape, Private Bag X17, Bellville 7535, South Africa

Received 3 July 2015; Accepted 26 August 2015

Academic Editor: Josefina Pons

Copyright © 2015 Natasha Ross et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. A. Thompson, “Latin Post,” 2015, http://www.latinpost.com/articles/47066.
  2. H. F. Günthard, J. A. Aberg, J. J. Eron et al., “Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society-USA panel,” The Journal of the American Medical Association, vol. 312, no. 4, pp. 410–425, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. H. Namme Luma, M.-S. Doualla, S.-P. Choukem et al., “Adverse drug reactions of Highly Active Antiretroviral Therapy (HAART) in HIV infected patients at the General Hospital, Douala, Cameroon: a cross sectional study,” The Pan African Medical Journal, vol. 12, p. 87, 2012. View at Google Scholar · View at Scopus
  4. V. Perrone, D. Cattaneo, S. Radice et al., “Impact of therapeutic drug monitoring of antiretroviral drugs in routine clinical management of patients infected with human immunodeficiency virus and related health care costs: a real-life study in a large cohort of patients,” ClinicoEconomics and Outcomes Research, vol. 6, no. 1, pp. 341–348, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. A. I. Cederbaum, “Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications,” Redox Biology, vol. 4, pp. 60–73, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Fasan, “Tuning P450 enzymes as oxidation catalysts,” ACS Catalysis, vol. 2, no. 4, pp. 647–666, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. D.-H. Zhang, L.-X. Yuwen, and L.-J. Peng, “Parameters affecting the performance of immobilized enzyme,” Journal of Chemistry, vol. 2013, Article ID 946248, 7 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Rahman, X.-B. Li, N. S. Lopa, S. J. Ahn, and J.-J. Lee, “Electrochemical DNA hybridization sensors based on conducting polymers,” Sensors, vol. 15, no. 2, pp. 3801–3829, 2015. View at Publisher · View at Google Scholar
  9. Z. Wang, N. Sun, Y. He, Y. Liu, and J. Li, “DNA assembled gold nanoparticles polymeric network blocks modular highly sensitive electrochemical biosensors for protein kinase activity analysis and inhibition,” Analytical Chemistry, vol. 86, no. 12, pp. 6153–6159, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Valentini and G. Palleschi, “Nanomaterials and analytical chemistry,” Analytical Letters, vol. 41, no. 4, pp. 479–520, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Okawa, N. Yokoyama, Y. Sakai, and F. Shiba, “Direct electron transfer biosensor for hydrogen peroxide carrying nanocomplex composed of horseradish peroxidase and Au-nanoparticle—characterization and application to bienzyme systems,” Analytical Chemistry Research, vol. 5, pp. 1–8, 2015. View at Publisher · View at Google Scholar
  12. W. Putzbach and N. J. Ronkainen, “Immobilization techniques in the fabrication of nanomaterial-based electrochemical biosensors: a review,” Sensors, vol. 13, no. 4, pp. 4811–4840, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. H. Mallin, J. Muschiol, E. Byström, and U. T. Bornscheuer, “Efficient biocatalysis with immobilized enzymes or encapsulated whole cell microorganism by using the SpinChem reactor system,” ChemCatChem, vol. 5, no. 12, pp. 3529–3532, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. R. A. Sheldon, M. J. Sorgedrager, and M. H. A. Janssen, “Use of cross-linked enzyme aggregates (CLEAs) for performing biotransformations,” Chemistry Today, vol. 25, pp. 62–67, 2007. View at Google Scholar
  15. N. R. Mohamad, N. H. Marzuki, N. A. Buang, F. Huyop, and R. A. Wahab, “An overview of technologies for immobilization of enzymes and surface analysis techniques for immobilized enzymes,” Biotechnology & Biotechnological Equipment, vol. 29, no. 2, pp. 205–220, 2015. View at Publisher · View at Google Scholar
  16. P. Zucca and E. Sanjust, “Inorganic materials as supports for covalent enzyme immobilization: methods and mechanisms,” Molecules, vol. 19, no. 9, pp. 14139–14194, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. I. Ince, C. A. J. Knibbe, M. Danhof et al., “A novel maturation function for clearance of the cytochrome P450 3A substrate midazolam from preterm neonates to adults,” Clinical Pharmacokinetics, vol. 52, no. 7, pp. 555–565, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. K. Ariga, Q. Ji, T. Mori et al., “Enzyme nanoarchitectonics: organization and device application,” Chemical Society Reviews, vol. 42, no. 15, pp. 6322–6345, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Sasso, A. Heiskanen, F. Diazzi et al., “Doped overoxidized polypyrrole microelectrodes as sensors for the detection of dopamine released from cell populations,” Analyst, vol. 138, no. 13, pp. 3651–3659, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. B. G. Kalzung, S. B. Masters, and A. J. Trevor, Eds., Basic & Clinical Pharmacology, McGraw-Hill Medical, New York, NY, USA, 11th edition, 2010.
  21. A. Ignaszak, N. Hendricks, T. Waryo et al., “Novel therapeutic biosensor for indinavir—a protease inhibitor antiretroviral drug,” Journal of Pharmaceutical and Biomedical Analysis, vol. 49, no. 2, pp. 498–501, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Björninen, A. Siljander, J. Pelto et al., “Comparison of chondroitin sulfate and hyaluronic acid doped conductive polypyrrole films for adipose stem cells,” Annals of Biomedical Engineering, vol. 42, no. 9, pp. 1889–1900, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Fakhry, H. Cachet, and C. D. Chouvy, “Electrochemical characterisations of ultra thin overoxidized polypyrrole films obtained by one-step electrosynthesis,” Journal of the Electrochemical Society, vol. 160, no. 10, pp. D465–D470, 2013. View at Publisher · View at Google Scholar
  24. E. A. Schneider, Oriented attachment of cytochrome P450 2C9 to a self-assembled monolayer on a gold electrode as a biosensor design [Ph.D. thesis], University of California, San Francisco, Claif, USA, 2011.
  25. C. Baj-Rossi, G. De Micheli, and S. Carrara, “Electrochemical detection of anti-breast-cancer agents in human serum by cytochrome p450-coated carbon nanotubes,” Sensors, vol. 12, no. 5, pp. 6520–6537, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. N. R. Hendricks, T. T. Waryo, O. Arotiba, N. Jahed, P. G. L. Baker, and E. I. Iwuoha, “Microsomal cytochrome P450-3A4 (CYP3A4) nanobiosensor for the determination of 2,4-dichlorophenol—an endocrine disruptor compound,” Electrochimica Acta, vol. 54, no. 7, pp. 1925–1931, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. E. I. Iwuoha, R. Ngece, M. Klink, and P. Baker, “Amperometric responses of CYP2D6 drug metabolism nanobiosensor for sertraline: a selective serotonin reuptake inhibitor,” IET Nanobiotechnology, vol. 1, no. 4, pp. 62–67, 2007. View at Publisher · View at Google Scholar · View at Scopus