Table of Contents Author Guidelines Submit a Manuscript
Journal of Chemistry
Volume 2015, Article ID 925654, 8 pages
http://dx.doi.org/10.1155/2015/925654
Research Article

Evaluation of Ethnopharmacological and Antioxidant Potential of Zanthoxylum armatum DC.

Department of Botany, PMAS Arid Agriculture University Rawalpindi, Rawalpindi 46000, Pakistan

Received 26 November 2014; Revised 25 January 2015; Accepted 4 February 2015

Academic Editor: Deniz Ekinci

Copyright © 2015 Rabia Kanwal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Zanthoxylum armatum DC. (syn. Z. alatum Roxb.) is an important medicinal plant commonly called Timur or Indian prickly ash. The ethnopharmacological study of Z. armatum revealed the use of different plant parts for curing various ailments including cholera, chest infection, fever, indigestion, stomach disorders, gas problems, piles, toothache, gum problems, dyspepsia, as carminative, antipyretic, aromatic, tonic, and stomachic. Keeping in view the medicinal potential of the plant, the antioxidant activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reducing power, and phosphomolybdate assay using different concentrations (7.81 μg/mL–250 μg/mL). Ascorbic acid was taken as standard. The results indicated that the free radical scavenging activity ranged from 40.12% to 78.39%, and the reductive potential ranged from 0.265 nm to 1.411 nm while the total antioxidant activity ranged from 0.124 nm to 0.183 nm. The antioxidant potential evaluated by three assays increased in a concentration dependent manner and ascorbic acid showed better antioxidant activity than leaf extract. Results obtained through different tests confirmed redox protective activities of Zanthoxylum armatum. Further in vitro and in vivo research should be performed, so this plant can be further utilized in drug development.