Source Health benefits Reference Extracted polyphenol Prevention of oxidative stress related diseases including diabetes [86 ] Tannins Scavenging action against active oxygen free radicals [82 , 87 , 88 ] Tannin Assists the neuronal degeneration and karyopyknosis in cells, reduction of thickness of skin epidermis [89 ] Flavonoids Scavenging action against active oxygen free radicals [82 , 87 , 88 ] Persimmon fruit Whole fruit Possesses antitumor effects due to betulinic acid [47 , 90 ] Blood pressure-lowering and diuretic effects, also effective for coughs treatment [91 ] Has antioxidative potentials due to compounds like vitamin A, beta-carotene, lycopene, lutein, zeaxanthin, and cryptoxanthin [92 ] Exhibits hypolipidemic and antioxidant properties [50 , 82 ] Contains nutritional antioxidant vitamins, polyphenols, and dietary fiber [93 , 94 ] Reduction of patches of pigmentation on skin [95 ] Has ability to dilate the blood vessels near the surface of the skin, thereby allowing more blood to flow through the skin, where it can be cooled by the air (antifebrile) [96 ] Reduction of degenerative disease in human beings [91 , 97 –99 ] Fruit peel powder Pharmacological potential such as antioxidant and hypocholesterolemic
[51 , 95 , 100 ] Water-soluble polysaccharides extracted from persimmon fruits Have ability to alter or regulate immune functions (immunomodulatory activity) [85 ] Persimmon vinegar Has antitumor and antioxidative effects and also prevents metabolic disorder induced by chronic alcohol administration [101 ] Plant and leaf extracts Persimmon leaf tea Prevents hardening of the arteries which ultimately lowers the blood pressure [95 ] Good source of natural antioxidants [102 ] Persimmon plant extracts Contain antitumor and multidrug resistance-reversing agents [47 ] Persimmon calyx extracts Anticonvulsants [103 ] Persimmon plant supplemented to a diet Hypocholesterolemic and antioxidative effects [82 ] Persimmon seeds Contain omega 6 fatty acids like palmitic acid, oleic acid, and linoleic acid [63 ] Radical-scavenging activity [104 ]
