Theoretical Study of Phosphoethanolamine: A Synthetic Anticancer Agent with Broad Antitumor Activity

Table 1

Calculated and molar refractivity of phosphoethanolamine and analogues, phosphoethanolamine metabolites, and group of 8 organophosphorus compounds. Pho: phosphoethanolamine; Pho_01 to Pho_03: phosphoethanolamine analogues; M1 to M8: phosphoethanolamine metabolites; O1: Chlorpyrifos-Oxon; O2: O,O-dibutyl O-(2,2-dichlorovinyl) Phosphate; O3: Paraoxon; O4: Cyclic Tolyl Saligenin Phosphate; O5: Diisopropyl Phosphorofluoridate; O6: Cyclic Phenyl Saligenin Phosphate; O7: Dichlorvos; O8: Trichlorfon.

Compound	c	Molar refractivity
Pho	−2.05	25.25
Pho_01	−0.26	43.71
Pho_02	1.24	63.28
Pho_03	2.35	73.77
M1	−2.02	37.51
M2	−1.60	23.63
M3	−2.40	25.46
M4	−1.87	22.71
M5	−1.95	23.59
M6	−2.41	38.54
M7	−2.45	26.28
M8	−2.52	27.22
O1	3.78	75.46
O2	3.18	66.21
O3	3.69	71.25
O4	1.37	52.19
O5	1.76	40.89
O6	4.02	79.94
O7	2.43	63.69
O8	1.14	47.59