Research Article

Highly Sensitive Micellar Enhanced Spectrofluorimetric Method for Determination of Mirtazapine in Tablets and Human Urine: Application to In Vitro Drug Release and Content Uniformity Test

Table 4

Robustness of the proposed spectrofluorimetric method.

Experimental parameter variationRecovery (%) ± SD

No variation99.68 ± 0.88
SLS volume (µL)
 28096.19 ± 1.23
 320101.51 ± 1.34
Acid concentration (N)
 0.0897.81 ± 1.26
 0.1299.19 ± 1.51
Acid volume (µL)
 18099.07 ± 0.61
 220102.05 ± 1.15
Temperature (C°)
 20104.04 ± 1.67
 3097.22 ± 1.08

Mean of three determinations,  following the general calibration procedures.