Design Synthesis and Biological Evaluation of Novel N-Nitro Acid Amide Derivatives as Lead Compounds of Herbicide

Table 2

The IC₅₀ values results summary of candidate compounds against AHAS.

Number	IC50 (mg/L)
Nicosulfuron	0.068
I-1	21.06
I-2	29.75
II-1	23.52
II-2	37.6
II-3	28.66
II-4	28.25
II-5	36.2
II-6	10.43
	394.41
II-8	24.35
	273.38
II-10	7.09
	252.81
II-12	14.28
II-13	12.53
II-14	19.93
	301.96
	509.66
II-17c	14.64
	393.12
II-19	17.01
II-20	18.15
II-21	9.07
II-22	9.11

The concentrations of the “” target compounds were 100 mg/L, 200 mg/L, 300 mg/L, 400 mg/L, and 500 mg/L. The concentrations of the nicosulfuron were 0.01 mg/L, 0.025 mg/L, 0.05 mg/L, 0.075 mg/L, and 0.1 mg/L. The concentrations of the rest of the target compounds were 1 mg/L, 5 mg/L, 10 mg/L, 25 mg/L, and 50 mg/L.