Comparison of Neuroprotective and Cognition-Enhancing Properties of Hydrolysates from Soybean, Walnut, and Peanut Protein
Table 3
Effects of SPH, WPH, and PPH on memory acquisition, consolidation, and retrieval in normal mice in step-down test in normal and anisodine-treated mice.
(a)
Sample
OM
CM
RM
WT in 5 min
LP (min)
Percentage of WRA (%)
WT in 3 min
LP (min)
Percentage of WRA (%)
WT in 3 min
LP (min)
Percentage of WRA (%)
Control
1.1 1.1
2.10 1.25
73.3
0.8 1.1
2.11 1.05
46.7
1.1 1.1
1.63 1.31
60.0
Piracetam
1.0 1.1
3.20 1.81
53.3
0.5 0.7
2.33 0.86
40.0
0.2 0.4
2.85 0.33
20.0
SPH
0.8 1.0
3.08 2.13
46.7
0.8 0.9
2.01 1.04
53.3
0.3 0.8
2.76 0.66
20.0
WPH
0.5 0.6
3.15 2.07
46.7
0.5 0.7
2.30 1.03
33.3
0.1 0.4
2.72 0.78
13.3
PPH
1.3 1.0
2.20 1.51
73.3
0.4 0.6
2.38 0.91
33.3
0.2 0.4
2.85 0.33
20.0
(b)
Sample
OM
CM
RM
WT in 5 min
LP (min)
Percentage of WRA (%)
WT in 3 min
LP (min)
Percentage of WRA (%)
WT in 3 min
LP (min)
Percentage of WRA (%)
Control
3.4 2.8
2.22 1.52
80.0
1.2 1.1
1.79 1.22
60.0
0.9 1.7
2.38 0.94
33.3
Piracetam
2.8 3.5
2.34 1.94
80.0
0.6 1.1
3.83 1.83
33.3
0.3 0.6
4.22 1.36
26.7
SPH
1.9 2.6
2.32 2.08
60.0
0.3 0.6
2.74 0.72
20.0
0.5 0.7
2.69 0.73
33.3
WPH
3.7 3.6
1.51 1.74
56.7
0.5 1.1
2.73 0.59
20.0
0.8 1.1
2.45 0.80
53.3
PPH
3.5 2.8
1.32 1.54
53.3
0.5 0.6
2.65 0.48
40.0
0.3 0.7
2.81 0.55
20.0
Note: step-down test results (a) in normal mice trial and (b) in anisodine-treated mice trials. OM, obtained memory group; CM, consolidated memory group; RM, recurred memory group; WT, wrong times of jumping out of the platform; ESA, electric shocked animals; WRA, wrong reactive animals; LP, the latent period of first jumping. Each value indicates mean SD (). p < 0.05 and p < 0.01, compared with control (-test).
