Research Article
Application and Validation of Simple Isocratic HPLC-UV-DAD Method with Dual Wavelength Detection for Ivabradine Determination and Its Application in the Study of Stress Degradation
Figure 4
Chromatographic set showing degradation products generated in various conditions at 286 nm: (a) thermal degradation (solution), (b) thermal degradation (powder), (c) acid degradation, (d) alkaline degradation, (e) oxidation (3% H2O2), (f) oxidation (7.5% H2O2), (g) oxidation (15% H2O2), (h) photolysis (24 h), (i) photolysis (48 h), and (j) photolysis (powder, 120 h).
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