Research Article
New Caffeic Acid Phenylethyl Ester Analogs Bearing Substituted Triazole: Synthesis and Structure-Activity Relationship Study towards 5-Lipoxygenase Inhibition
Scheme 2
Synthesis of series 2: (i): NaN3, DMSO, rt, overnight; (ii) 6, CuSO45H2O, sodium ascorbate, H2O, rt, overnight (10a: 65%; 10b: 65%; 10c: 63%; 10d: 47%; 10e: 68%; 10f: 53%).