Research Article

Solvent-Free Henry and Michael Reactions with Nitroalkanes Promoted by Potassium Carbonate as a Versatile Heterogeneous Catalyst

Table 3

Henry reaction using 10 mol% K2CO3 at 60°C.

EntryRR1R2Time
(h)
Yield of 3 (%)

aCH3CH3H448
bCH3CH2CH2CH3CH3546
cCH3HH4.575
dPhCH3H4.560
eCH3CH3CH3448
fPhCH2n-C2H5H550
gCH3CH2CH2CH2n-C2H5H4.560
hPhCH2CH2n-C3H7H6.558
in-C5H11n-C3H7H872
jp-NO2C6H4n-C4H9H7255
kPhHH3.560
lc-C6H11HH565
mp-OCH3C6H4HH2460
np-NO2C6H4HH466
oCH3BrH562

Yield of pure isolated product.
Reaction was carried out under CH2Cl2 solvent as the starting aldehyde was solid.