Ranitidine Loaded Biopolymer Floats: Designing, Characterization, and Evaluation

Table 1

Formulations design for RNT floats (drug 120 mg).

Batches	Materials (mg)	Low (−1)	Medium (0)	High (+1)	Constant
1st	ENa	100	150	200	NaHCO3 = 10
	SA	30	60	90	CA = 10
2nd	ENa	100	150	200	NaHCO3 = 10
	Tcanth	30	60	90	CA = 10
3rd	ENa	100	150	200	NaHCO3 = 10
	LSG	30	60	90	CA = 10
4th	ENa	100	150	200	NaHCO3 = 15
	PSG	30	60	90	CA = 10

LSG = linseed gel; PSG = psyllium seed gel; CHCl₃ = ⁱPrOH = 2 mL; TG = tragacanth gel; SA = stearic acid; CA = citric acid; HPMC: hydroxy propyl methyl cellulose; Mg stearate = 5 g to each float.