Response Surface Optimization of Rotenone Using Natural Alcohol-Based Deep Eutectic Solvent as Additive in the Extraction Medium Cocktail

Table 1

Response surface optimization run order actual and coded value.

Run order	Actual value			Coded value
	:	:	:	:	:	:
	Solvent ratio (DES : acetonitrile)	Extraction time (hour)	Agitation rate (rpm)	Solvent ratio	Extraction time (hour)	Agitation rate (rpm)
1	8 : 2	19.34	50.67
2 (CP)	5 : 5	12.50	125.00
3	8 : 2	19.34	199.33
4 (CP)	5 : 5	12.50	125.00
5 (CP)	5 : 5	12.50	125.00
6	5 : 5	12.50	250.00
7 (CP)	5 : 5	12.50	125.00
8 (CP)	5 : 5	12.50	125.00
9	1 : 0	12.50	125.00
10	5 : 5	24.00	125.00
11	5 : 5	1.00	125.00
12	2 : 8	5.66	199.33
13	5 : 5	12.50	0.00
14	2 : 8	19.34	199.33
15	2 : 8	5.66	50.67
16	8 : 2	5.66	199.33
17	2 : 8	19.34	50.67
18	0 : 1	12.50	125.00
19 (CP)	5 : 5	12.50	125.00
20	8 : 2	5.66	50.67