Research Article

Synthesis and Biological Evaluation of 1,3,8-Triazaspiro[4.5]decane-2,4-dione Derivatives as Myelostimulators

Table 1

The proportions of reagents used in the synthesis of 8-(2-ethoxyethyl-,3-ethoxypropyl-,3-butoxypropyl-)-6-(Н, methyl)-1,3,8-triazaspiro[4.5]decane-2,4-diones.

CompoundReagent amount, mol
4-Piperidone(NH4)2CO3NaCN

30.0400.0820.053
80.0380.0760.046
90.0250.1900.050
100.0330.0660.043
110.0480.1900.096