Journal of Chemistry / 2018 / Article / Tab 1

Research Article

Microfluidic Preparation of Liposomes Using Ethyl Acetate/n-Hexane Solvents as an Alternative to Chloroform

Table 1

Physicochemical properties of chloroform and nonhalogenated solvents.

Chloroformn-HexaneEthyl acetateAcetoneIsopropanolMethanolDiethyl etherMethyl acetateBenzene

Polarity index4.100.104.405.103.905.102.804.403.00
Solubility in water (g/100 mL)0.820.008.70MiscibleMiscibleMiscible6.9024.400.18
Viscosity (cP)0.570.330.450.322.300.550.220.360.61
Vapor pressure (kPa)25.9017.609.7330.606.0213.0258.6623.0612.70
Lecithin solubilitySSSSSISIS
Allowable concentration (g/kg)Prohibited0.010.050.030.050.05ProhibitionProhibitionProhibition

S, soluble; I, insoluble.

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