Research Article
Synthesis, Antibacterial Evaluation, and QSAR of Caffeic Acid Derivatives
Table 1
Minimal inhibitory concentration (MIC) values (expressed in µM) of the compounds 1–16.
| Compounds | MIC (µM) | Staphylococcus aureus (ATCC-25619) | Escherichia coli (ATCC-2536) |
| 1 | 0.52 | 0.52 | 2 | 0.48 | 0.48 | 3 | 0.45 | 0.22 | 4 | 0.45 | 0.45 | 5 | 0.84 | 0.84 | 6 | 0.21 | 0.21 | 7 | 0.40 | 0.20 | 8 | 0.80 | 0.40 | 9 | 0.62 | 0.62 | 10 | 0.58 | 0.29 | 11 | 1.31 | 1.31 | 12 | 0.67 | 0.33 | 13 | 0.93 | 0.23 | 14 | 0.95 | 0.48 | 15 | 0.74 | 0.37 | 16 | 1.41 | 0.70 | Chloramphenicol | 0.31 | 0.31 |
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