Palladium-Catalyzed C(sp³)-H Arylation of Benzo[b]thiophen-3(2H)-one 1,1-Dioxide

Table 1

Optimization of phosphine ligands.

Entry^1	Ligand	Yield (%)^2
1	L1	60
2	L2	53
3	L3	37
4	L4	47
5	L5	35
6	L6	11
7	L7	39
8	L8	38
9	L9	17
10	L10	NR
11	No ligand	NR

¹Reaction conditions: 10 mol% of Pd(OAc)₂, 20 mol% of ligand, 0.25 mmol of 1a, 0.5 mmol of 1b, 0.75 mmol of KO^tBu, and 1 mL of toluene, 110°C, 24 h. ²GC yield.