TY - JOUR A2 - Navarrete-Vazquez, Gabriel AU - Achakzai, Jahangir Khan AU - Anwar Panezai, Muhammad AU - Kakar, Abdul Manan AU - Akhtar, Basira AU - Akbar, Ali AU - Kakar, Shahabuddin AU - Khan, Javed AU - Khan, Nazima Yousaf AU - Khan, Ghulam Mustafa AU - Baloch, Nizam AU - Jan Khoso, Muhammad Hashim AU - Panezai, Marina PY - 2019 DA - 2019/10/01 TI - In Vitro Antileishmanial Activity and GC-MS Analysis of Whole Plant Hexane Fraction of Achillea wilhelmsii (WHFAW) SP - 5734257 VL - 2019 AB - In this study, GC-MS analysis has shown that whole plant hexane fraction of Achillea wilhelmsii (WHFAW) consists of 66 compounds which exhibited antileishmanial activity. Antileishmanial bioassay was the method used for determining antileishmanial activity. The inhibitory concentration (IC50) which was observed for whole plant hexane fraction of Achillea wilhelmsii (WHFAW) against parasitic and vector-borne disease, leishmaniasis, is 58.27 ± 0.52 μg/mL. For leishmanicidal assay, Leishmania major is the species used for analysis. Whole plant methanol extract of Achillea wilhelmsii (WMEAW) and whole plant aqueous fraction of Achillea wilhelmsii (WAFAW) exhibited no antileishmanial activity. SN - 2090-9063 UR - https://doi.org/10.1155/2019/5734257 DO - 10.1155/2019/5734257 JF - Journal of Chemistry PB - Hindawi KW - ER -