Research Article
Synthesis of Phenols via Metal-Free Hydroxylation of Aryl Boronic Acids with Aqueous TBHP
Table 3
Substrate scope for the direct hydroxylation of aryl boronic acidsa.
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aReaction conditions: aryl boronic acid (1 mmol), aqueous TBHP (2 mmol), TBHP (2 mmol), KOtBu (1 mmol), and H2O (1 mL), 50°C; bisolated yield; cproducts were characterized by MP, FTIR, and 1H- and 13C-NMR; dthe desired product was not isolated; eCharacterized by FTIR. |