Synthesis of 1,2-Dihydro-Substituted Aniline Analogues Involving N-Phenyl-3-aza-Cope Rearrangement Using a Metal-Free Catalytic Approach

Table 2

Scope of the annulation reaction of N-propargyl vinyl anilines.

Entry	Propargyl acetate	Aniline	Michael acceptors^a	Propargyl vinyl amine	1,2-Dihydropyridine	Yield (%)^b
1		Aniline	a			95
2		p-Anisidine	a			88
3		4-Bromo aniline	a			76
4		p-Anisidine	b			48
5		p-Anisidine	b			56
6		Aniline	a			81
7		p-Anisidine	b			85
8		Aniline	b			70
9		p-Anisidine	b			84
10		Aniline	b			92
11		Aniline	c			68
12		Aniline	c			61

a, ; b, ; c, ; isolated yields by column chromatography.