Optimization of Extraction Process of Methyl Eugenol and Asarinin in Asarum with Deep Eutectic Solvent Based on the Response Surface Methodology

Table 6

Analysis of variance of the regression model.

Source	Sum of squares	Df	Mean square	F value	value
Model	2.32	14	0.17	16.50	<0.0001	Significant
A. Molar ratio	0.30	1	0.30	29.41	<0.0001
B. DES volume	0.031	1	0.031	3.07	0.1018
C. Ultrasonic temperature	9.883E-003	1	9.883E-003	0.98	0.3379
D. Ultrasonic time	6.961E-003	1	6.961E-003	0.69	0.4190
AB	0.11	1	0.11	10.93	0.0052
AC	2.923E-003	1	2.923E-003	0.29	0.5980
AD	3.300E-003	1	3.300E-003	0.33	0.5755
BC	4.308E-003	1	4.308E-003	0.43	0.5230
BD	4.436E-003	1	4.436E-003	0.44	0.5170
CD	3.930E-003	1	3.930E-003	0.39	0.5416
A2	1.77	1	1.77	176.57	<0.0001
B2	6.459E-003	1	6.459E-003	0.64	0.4359
C2	1.500E-003	1	1.500E-003	0.15	0.7049
D2	0.013	1	0.013	1.32	0.2692
Residual	0.14	14	0.010
Lack of fit	0.12	10	0.012	2.30	0.2187	Not significant
Pure error	0.021	4	5.199E-003
Cor. total	2.46	28
R2	0.9429
R2Adj	0.8857
CV (%)	5.01
Adeq precision	12.372