Isolation and In Silico Anti-COVID-19 Main Protease (M^pro) Activities of Flavonoids and a Sesquiterpene Lactone from Artemisia sublessingiana

Table 1

The docking binding free energies of seven compounds, simeprevir, and the cocrystallized ligand (PRD-002214) against COVID-19 main protease.

Compound	Binding free energy (kcal/mol)
1	−6.53
2	−6.81
3	−6.51
4	−6.44
5	−6.39
6	−6.55
7	−4,94
Cocrystallized ligand (PRD-002214)	−7.83