Chiral Resolution, Absolute Configuration Assignment, and Genotoxicity Evaluation of Racemic 3,4-Dihydroquinazoline as a Novel Anticancer Agent

Figure 2

Chiral HPLC spectra, specific optical rotations, and enantiomeric excess (ee) of the racemate (±)-KCP-10043F (OZ-001) and its two enantiomers: (a) racemate (±)-KCP-10043F (OZ-001); (b) (+)-KCP-10043F; (c) (−)-KCP-10043F.

(a)

(b)

(c)