Substituted-Amidine Functionalized Monocyclic <i>β</i>-Lactams: Synthesis and <i>In Vitro</i> Antibacterial Profile

<div>Synthesis of compound <b>14g</b>. Reagents and conditions: (a) <b>12a</b>, HOBT, DCC, NaHCO<sub>3</sub>, DMF, 0°C – rt, 69%; (b) TFA, CH<sub>2</sub>Cl<sub>2</sub>, 0°C – rt, 11%.</div>

Journal of Chemistry

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Scheme 3

Scheme 3: Substituted-Amidine Functionalized Monocyclic <i>β</i>-Lactams: Synthesis and <i>In Vitro</i> Antibacterial Profile 

Journal of Chemistry

Substituted-Amidine Functionalized Monocyclic β-Lactams: Synthesis and In Vitro Antibacterial Profile

Scheme 3