Novel α-Mangostin Derivatives from Mangosteen (Garcinia mangostana L.) Peel Extract with Antioxidant and Anticancer Potential

Figure 1

(a) Structures of α-MG and its natural derivatives, including ß-MG and γ-MG. (b) Examples of α-MG derivatives at position C3 and C6 with biological activity [47]. (i) 1-Hydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-6-(((R)-oxiran-2-yl)methoxy)-3-(((S)-oxiran-2-yl)methoxy)-9H-xanthen-9-one, (ii) 3,6-bis(4-aminobutoxy)-1-hydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, and (iii) 3,6-bis(4-(diethylamino)butoxy)-1-hydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one [48, 49].