Research Article

An In Silico Study of the Interactions of Alkaloids from Cryptolepis sanguinolenta with Plasmodium falciparum Dihydrofolate Reductase and Dihydroorotate Dehydrogenase

Figure 5

Interactions of some alkaloids with wt-PfDHFR: 3D (left) and 2D (right) views of the interactions of (a) hydroxycryptolepine and (b) cryptolepine with residues in the binding region of wild-type PfDHFR (3QGT). Description of interactions is provided under 2D images.
(a)
(b)