Two-dimensional (2D) materials are layer-structured materials. When comprised of only one or a few layers, they have been shown to have unique properties that differ from the bulk material. In the past decade, 2D materials have shown promise in bio- or chemical sensing and environmental monitoring, such as graphene-based sensors for detection of heavy metal ions and organic pollutants, and MoS₂-based biosensors for detection of biomolecules and pathogenic microorganisms. Recently, there has been an increasing interest in the use of 2D materials in biomedical applications, such as targeted drug delivery, bioimaging, and tissue engineering. This interest has come as a result of the recent advances in the synthesis and characterization of 2D materials.

This special issue will summarize the synthesis and characterization of 2D materials and their applications in chemical, biological, and environmental sensing. We hope that this special issue will provide interdisciplinary insights and outline the current challenges in the study and creation of 2D materials. Both original articles and reviews highlighting the current research are welcome.

Potential topics include but are not limited to the following:

• Synthesis and/or characterization of 2D materials
• Functionalization and patterning methods of 2D materials
• Electrochemical-related applications of 2D materials for use in sensing
• Demonstrations of bio- or chemical sensors or articles comparing the strengths and weaknesses of different 2D materials for sensing
• Biocompatibility, toxicity, and environmental impact studies of 2D materials
• Applications of 2D materials for environmental sensing of water, air, and soil quality