Journal of Chemistry

Fluorescent Probes: Current and Future Trends

Publishing date
01 Jan 2020
Submission deadline
30 Aug 2019

1University of Trento, Trento, Italy

2University of Münster, Münster, Germany

This issue is now closed for submissions.
More articles will be published in the near future.

Fluorescent Probes: Current and Future Trends

This issue is now closed for submissions.
More articles will be published in the near future.


Fluorescent probes are indispensable tools for the detection and quantification of chemical and biological molecules. Throughout the last few decades, fluorescence was exploited for the identification of trace amounts of innumerable organic and inorganic molecules with great sensitivity and selectivity. The availability of probes for a specific ion or molecule often gave rise to extraordinary advancements of an entire field, as exemplified by Fura-2 and its derivates and the FRET-based calcium biosensors.

The revolutionary and rapid advance of fluorescence imaging techniques (e.g., laser scanning confocal and two-photon microscopy) have provided better insight into the molecular processes in living organisms with high sensitivity, simplicity, and fast response. All these techniques have facilitated the development of novel fluorescent probes and sensors. Nowadays, a wide range of fluorescent probes are available and used as powerful tools to detect, localize, and study the dynamics of biomolecules including ions, proteins, analytes, lipids, cofactors, and drugs, to target various cellular organelles, to analyze environmental contaminants and for food quality analysis. However, despite the wide field of application, new fluorescent probes are needed to better understand cell physiology and natural processes.

This special issue is intended to be an up-to-date and comprehensive issue focused on fluorescent probes and aims to pave the way to future developments in this wide and dynamic field. We cordially invite you to submit original papers, short communications, perspectives, critical overviews, and reviews directed, but not limited, to the design, synthesis, and characterization of fluorescent probes potentially implicated in biotechnological, medicine, and medicinal chemistry applications. All aspects of the topics are welcome, including new fluorescent compounds and their applications, novel discoveries, imaging and data for especially challenging targets, and new fluorescence-based techniques to advance the field. Reviews should provide a retrospective analysis and a critical overview of the current state-of-the-art, highlighting the recent advances of this wide field.

Potential topics include but are not limited to the following:

  • Fluorescent sensing mechanisms
  • Synthesis and application of fluorescent probes
  • The applications of fluorescent probes in medicinal chemistry
  • Fluorescent probe based nanomaterials
  • Spectroscopic-based biosensors
  • Studies on Förster resonance energy transfer (FRET)
  • Ion fluorescence indicator dyes and metal enhanced fluorescence (MEF)
  • One photon/two-photon excitable probes
  • Ratiometric near-infrared fluorescent probes
  • Fluorescent detection and the resulting biomedical applications
Journal of Chemistry
 Journal metrics
Acceptance rate32%
Submission to final decision81 days
Acceptance to publication50 days
Impact Factor1.727

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.