CXCR4 Expression in Gastric Cancer and Bone Marrow: Association with Hypoxia-Regulated Indices, Disseminated Tumor Cells, and Patients Survival

Table 1

Prevalence of CXCR4⁺ in gastric cancer tissue by clinical variables.

Characteristics	All patients number; ()	CXCR4^+  number; ()	CXCR4^−  number; ()
Age, median (range) (years)	63 (26–77)	61 (26–77)	63 (34–73)
Gender
Male	44	36	8	0.3406
Female	21	15	6
Histological type
Adenocarcinoma	47	36	11	0.6985
Mucinous adenocarcinoma	7	5	2
Signet-ring cell carcinoma	9	8	1
Undifferentiated carcinoma	2	2	0
Tumor location
Upper third	5	3	2	0.1201
Middle third	17	12	5
Lower third	36	32	4
Total	7	4	3
Grade (G)
1	4	3	1	0.3263
2	13	12	1
3	44	32	12
4	4	4	0
UICC stage
I	17	12	5	0.6471
II	15	13	2
III	20	15	5
IV	13	11	2
T-classification
T1	7	7	0	0.3862
T2	17	12	5
T3	28	21	7
T4	13	11	2
Nodal involvement
N0	36	28	8	0.8812
N1-2	29	23	6
Distant metastasis
M0	57	44	13	0.5066
M1	8	7	1