Effects of Selected Anionic β-Cyclodextrins on Persistence of Blood Glucose Lowering by Insulin Glargine after Subcutaneous Injection to Rats
Effects of Sul-β-CyD and SBE7-β-CyD (10 mM) on permeation of insulin glargine (0.1 mM) through ultrafiltration membrane having nominal molecular weight limit of 30,000 in phosphate buffer (pH 9.5, I = 0.2) at 25°C. Each value represents the mean ± S.E.M. of 17 and 5 experiments for insulin glargine and with Sul-β-CyD or SBE7-β-CyD, respectively. *, compared to insulin glargine. #, compared to Sul-β-CyD.
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