Effects of Selected Anionic β-Cyclodextrins on Persistence of Blood Glucose Lowering by Insulin Glargine after Subcutaneous Injection to Rats

Table 1

Particle size of insulin glargine with or without Sul-β-CyD and SBE7-β-CyD (10 mM) in phosphate buffer (pH 9.5). The particle size was measured by a Zetasizer Nano. The concentrations of insulin glargine and β-CyDs were 0.1 mM and 10 mM, respectively. Each value represents the mean ± S.E.M. of 5–7 experiments.

System	Diameter (nm)
Insulin glargine	744±82
With Sul-𝛽-CyD	1334±164^∗
With SBE7-𝛽-CyD	1575±228^∗

Uehata et al. [19]