Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery

Figure 1

MAb 734 binding with DTPA-indium hapten. Inhibition of DTPA-¹¹¹Indium binding to biotinylated MAb734 coated to avidin tubes as a function of DTPA-indium or EDTA-indium concentration. The equilibrium affinity constants were calculated from the data using standard Scatchard analysis.