Table of Contents Author Guidelines Submit a Manuscript
Journal of Drug Delivery
Volume 2011, Article ID 647631, 7 pages
http://dx.doi.org/10.1155/2011/647631
Research Article

Preparation of DNA/Gold Nanoparticle Encapsulated in Calcium Phosphate

1Research Institute of Pharmaceutical Sciences, Musashino University, Shinmachi 1-1-20, Nishitokyo-Shi, Tokyo 202-8585, Japan
2Graduate School of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-Shi, Chiba-Ken 278-8510, Japan

Received 27 October 2010; Revised 4 March 2011; Accepted 5 April 2011

Academic Editor: Guru V. Betageri

Copyright © 2011 Tomoko Ito et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. X. Zhou and L. Huang, “DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action,” Biochimica et Biophysica Acta, vol. 1189, no. 2, pp. 195–203, 1994. View at Publisher · View at Google Scholar · View at Scopus
  2. K. Taira, K. Kataoka, and T. Niidome, Eds., Non-Viral Gene Therapy: Gene Design and Delivery, Springer, Tokyo, Japan, 2005.
  3. S. M. Mel'nikov, V. G. Sergeyev, and K. Yoshikawa, “Discrete coil—globule transition of large DNA induced by cationic surfactant,” Journal of the American Chemical Society, vol. 117, no. 9, pp. 2401–2408, 1995. View at Google Scholar · View at Scopus
  4. C. Plank, K. Mechtler, F. C. Szoka Jr., and E. Wagner, “Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery,” Human Gene Therapy, vol. 7, no. 12, pp. 1437–1446, 1996. View at Google Scholar · View at Scopus
  5. Y. Koyama, T. Ito, H. Matsumoto et al., “Novel poly(ethylene glycol) derivatives with carboxylic acid pendant groups: synthesis and their protection and enhancing effect on non-viral gene transfection systems,” Journal of Biomaterials Science, Polymer Edition, vol. 14, no. 6, pp. 515–531, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. T. Ito, N. Iida-Tanaka, and Y. Koyama, “Efficient in vivo gene transfection by stable DNA/PEI complexes coated by hyaluronic acid,” Journal of Drug Targeting, vol. 16, no. 4, pp. 276–281, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. D. Olton, J. Li, M. E. Wilson et al., “Nanostructured calcium phosphates (NanoCaPs) for non-viral gene delivery: influence of the synthesis parameters on transfection efficiency,” Biomaterials, vol. 28, no. 6, pp. 1267–1279, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. C. Kneuer, M. Sameti, E. G. Haltner et al., “Silica nanoparticles modified with aminosilanes as carriers for plasmid DNA,” International Journal of Pharmaceutics, vol. 196, no. 2, pp. 257–261, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Niidome, M. Yamagata, Y. Okamoto et al., “PEG-modified gold nanorods with a stealth character for in vivo applications,” Journal of Controlled Release, vol. 114, no. 3, pp. 343–347, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Ghosh, G. Han, M. De, C. K. Kim, and V. M. Rotello, “Gold nanoparticles in delivery applications,” Advanced Drug Delivery Reviews, vol. 60, no. 11, pp. 1307–1315, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. G. Schmid, “Large clusters and colloids. Metals in the embryonic state,” Chemical Reviews, vol. 92, no. 8, pp. 1709–1727, 1992. View at Google Scholar · View at Scopus
  12. X. Huang, I. H. El-Sayed, W. Qian, and M. A. El-Sayed, “Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods,” Journal of the American Chemical Society, vol. 128, no. 6, pp. 2115–2120, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. I. H. El-Sayed, X. Huang, and M. A. El-Sayed, “Surface plasmon resonance scattering and absorption of anti-EGFR antibody conjugated gold nanoparticles in cancer diagnostics: applications in oral cancer,” Nano Letters, vol. 5, no. 5, pp. 829–834, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. T. Kawano, M. Yamagata, H. Takahashi et al., “Stabilizing of plasmid DNA in vivo by PEG-modified cationic gold nanoparticles and the gene expression assisted with electrical pulses,” Journal of Controlled Release, vol. 111, no. 3, pp. 382–389, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. S. V. Dorozhkin and M. Epple, “Biological and medical significance of calcium phosphates,” Angewandte Chemie—International Edition, vol. 41, no. 17, pp. 3130–3146, 2002. View at Publisher · View at Google Scholar · View at Scopus
  16. S. A. Redey, S. Razzouk, C. Rey et al., “Osteoclast adhesion and activity on synthetic hydroxyapatite, carbonated hydroxyapatite, and natural calcium carbonate: relationship to surface energies,” Journal of Biomedical Materials Research, vol. 45, no. 2, pp. 140–147, 1999. View at Publisher · View at Google Scholar · View at Scopus
  17. M. P. Ginebra, T. Traykova, and J. A. Planell, “Calcium phosphate cements as bone drug delivery systems: a review,” Journal of Controlled Release, vol. 113, no. 2, pp. 102–110, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. T. Kokubo and H. Takadama, “How useful is SBF in predicting in vivo bone bioactivity?” Biomaterials, vol. 27, no. 15, pp. 2907–2915, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Tanahashi and T. Matsuda, “Surface functional group dependence on apatite formation on self- assembled monolayers in a simulated body fluid,” Journal of Biomedical Materials Research, vol. 34, no. 3, pp. 305–315, 1997. View at Publisher · View at Google Scholar · View at Scopus