Table of Contents Author Guidelines Submit a Manuscript
Journal of Drug Delivery
Volume 2012, Article ID 143524, 13 pages
http://dx.doi.org/10.1155/2012/143524
Research Article

Glucan Particles for Macrophage Targeted Delivery of Nanoparticles

Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, MA 01605, USA

Received 1 June 2011; Revised 20 July 2011; Accepted 20 July 2011

Academic Editor: Rassoul Dinarvand

Copyright © 2012 Ernesto R. Soto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. S. Suri, H. Fenniri, and B. Singh, “Nanotechnology-based drug delivery systems,” Journal of Occupational Medicine and Toxicology, vol. 2, no. 1, pp. 1–6, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. R. A. Petros and J. M. DeSimone, “Strategies in the design of nanoparticles for therapeutic applications,” Nature Reviews Drug Discovery, vol. 9, no. 8, pp. 615–627, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. E. Brewer, J. Coleman, and A. Lowman, “Emerging technologies of polymeric nanoparticles in cancer drug delivery,” Journal of Nanomaterials, vol. 2011, Article ID 408675, 10 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. D. Sun, “Nanotheranostics: integration of imaging and targeted drug delivery,” Molecular Pharmaceutics, vol. 7, no. 6, p. 1879, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Ferrari, “Cancer nanotechnology: opportunities and challenges,” Nature Reviews Cancer, vol. 5, no. 3, pp. 161–171, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. M. E. Davis, Z. Chen, and D. M. Shin, “Nanoparticle therapeutics: an emerging treatment modality for cancer,” Nature Reviews Drug Discovery, vol. 7, no. 9, pp. 771–782, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. D. E. Owens III and N. A. Peppas, “Opsonization, biodistribution and pharmacokinetics of polymeric nanoparticles,” International Journal of Pharmaceutics, vol. 307, no. 1, pp. 93–102, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. J. A. Champion, Y. K. Katare, and S. Mitragotri, “Particle shape: a new design parameter for micro and nanoscale drug delivery carriers,” Journal of Controlled Release, vol. 121, no. 1-2, pp. 3–9, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. F. Alexis, E. Pridgen, L. K. Molnar, and O. C. Farokhzad, “Factors affecting the clearance and biodistribution of polymeric nanoparticles,” Molecular Pharmaceutics, vol. 5, no. 4, pp. 505–515, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. S. V. Vinogradov, T. K. Bronich, and A. V. Kabanov, “Nanosized cationic hydrogels for drug delivery: preparation, properties and interactions with cells,” Advanced Drug Delivery Reviews, vol. 54, no. 1, pp. 135–147, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. H. S. Choi, W. Liu, P. Misra et al., “Renal clearance of quantum dots,” Nature Biotechnology, vol. 25, no. 10, pp. 1165–1170, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. M. D. Howard, M. Jay, T. D. Dziubla, and X. Lu, “PEGylation of nanocarrier drug delivery systems: state of the art,” Journal of Biomedical Nanotechnology, vol. 4, no. 2, pp. 133–148, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. I. Hamad, A. C. Hunter, K. J. Rutt, Z. Liu, H. Dai, and S. M. Moghimi, “Complement activation by PEGylated single-walled carbon nanotubes is independent of C1q and alternative pathway turnover,” Molecular Immunology, vol. 45, no. 14, pp. 3797–3803, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. X. Wang, J. Li, Y. Wang et al., “HFT-T, a targeting nanoparticle, enhances specific delivery of paclitaxel to folate receptor-positive tumors,” ACS Nano, vol. 3, no. 10, pp. 3165–3174, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. P. S. Low, W. A. Henne, and D. D. Doorneweerd, “Discovery and development of folic acid based receptor targeting for imaging and therapy of cancer and inflammatory diseases,” Accounts of Chemical Research, vol. 41, no. 1, pp. 120–129, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. C. H. J. Choi, C. A. Alabi, P. Webster, and M. E. Davis, “Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles,” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 3, pp. 1235–1240, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. M. B. Dowling, L. Li, J. Park et al., “Multiphoton-absorption-induced-luminescence (MAIL) imaging of tumor-targeted gold nanoparticles,” Bioconjugate Chemistry, vol. 21, no. 11, pp. 1968–1977, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. L. Han, R. Huang, S. Liu, S. Huang, and C. Jiang, “Peptide-conjugated PAMAM for targeted doxorubicin delivery to transferrin receptor overexpressed tumors,” Molecular Pharmaceutics, vol. 7, no. 6, pp. 2156–2165, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. A. K. Patri, A. Myc, J. Beals, T. P. Thomas, N. H. Bander, and J. R. Baker, “Synthesis and in vitro testing of J591 antibody-dendrimer conjugates for targeted prostate cancer therapy,” Bioconjugate Chemistry, vol. 15, no. 6, pp. 1174–1181, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. C. Plank, K. Zatloukal, M. Cotten, K. Mechtler, and E. Wagner, “Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand,” Bioconjugate Chemistry, vol. 3, no. 6, pp. 533–539, 1992. View at Google Scholar · View at Scopus
  21. K. G. Neoh and E. T. Kang, “Functionalization of inorganic nanoparticles with polymers for stealth biomedical applications,” Polymer Chemistry, vol. 2, no. 4, pp. 747–759, 2011. View at Publisher · View at Google Scholar
  22. G. D. Brown and S. Gordon, “Immune recognition: a new receptor for β-glucans,” Nature, vol. 413, no. 6851, pp. 36–37, 2001. View at Google Scholar · View at Scopus
  23. H. Huang, G. R. Ostroff, C. K. Lee, J. P. Wang, C. A. Specht, and S. M. Levitz, “Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists,” Infection and Immunity, vol. 77, no. 5, pp. 1774–1781, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. E. R. Soto and G. R. Ostroff, “Characterization of multilayered nanoparticles inside yeast cell wall particles for DNA delivery,” Bioconjugate Chemistry, vol. 19, no. 4, pp. 840–848, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Aouadi, G. J. Tesz, S. M. Nicoloro et al., “Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation,” Nature, vol. 458, no. 7242, pp. 1180–1184, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. G. J. Tesz, M. Aouadi, M. Prot et al., “Glucan particles for selective delivery of siRNA to phagocytic cells in mice,” Biochemical Journal, vol. 436, no. 2, pp. 351–362, 2011. View at Publisher · View at Google Scholar
  27. E. Soto, Y. S. Kim, J. Lee, H. Kornfeld, and G. Ostroff, “Glucan particle encapsulated rifampicin for targeted delivery to macrophages,” Polymers, vol. 2, no. 4, pp. 681–689, 2010. View at Publisher · View at Google Scholar
  28. E. Soto and G. Ostroff, “Use of beta-1,3-D-glucans for drug delivery applications,” in Biology and Chemistry of Beta Glucan: Volume 1 Beta Glucans-Mechanisms of Action, V. Vetvicka and M. Novak, Eds., p. 82, Bentham Press, 2011. View at Google Scholar
  29. C. T. Kresge, M. E. Leonowicz, W. J. Roth, J. C. Vartuli, and J. S. Beck, “Ordered mesoporous molecular sieves synthesized by a liquid crystal template mechanism,” Nature, vol. 359, no. 6397, pp. 710–712, 1992. View at Google Scholar · View at Scopus
  30. B. G. Trewyn, I. I. Slowing, S. Giri, G. T. Chen, and V. S. Lin, “Synthesis and functionalization of a mesoporous silica nanoparticle based on the sol-gel process and applications in controlled release,” Accounts of Chemical Research, vol. 40, no. 9, pp. 846–853, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Liong, J. Lu, M. Kovovich et al., “Multifunctional Inorganic Nanoparticles for Imaging, Targeting and Drug Delivery,” ACSNano, vol. 2, no. 5, pp. 889–896, 2008. View at Google Scholar
  32. J. Lu, M. Liong, J. I. Zink, and F. Tamanoi, “Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs,” Small, vol. 3, no. 8, pp. 1341–1346, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. J. Lu, M. Liong, S. Sherman et al., “Mesoporous silica nanoparticles for cancer therapy: energy-dependent cellular uptake and delivery of paclitaxel to cancer cells,” Nanobiotechnology, vol. 3, no. 2, pp. 89–95, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. H. Zhao and N. D. Heindel, “Determination of degree of substitution of formyl groups in polyaldehyde dextran by the hydroxylamine hydrochloride method,” Pharmaceutical Research, vol. 8, no. 3, pp. 400–402, 1991. View at Publisher · View at Google Scholar · View at Scopus
  35. J. A. Willment, S. Gordon, and G. D. Brown, “Characterization of the human β-glucan receptor and its alternatively spliced isoforms,” Journal of Biological Chemistry, vol. 276, no. 47, pp. 43818–43823, 2001. View at Publisher · View at Google Scholar · View at Scopus
  36. A. S. Marshall, J. A. Willmen, H. H. Lin, D. L. Williams, S. Gordon, and G. D. Brown, “Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes,” Journal of Biological Chemistry, vol. 279, no. 15, pp. 14792–14802, 2004. View at Publisher · View at Google Scholar · View at Scopus
  37. T. Azzam, H. Eliyahu, L. Shapira, M. Linial, Y. Barenholz, and A. J. Domb, “Polysaccharide-oligoamine based conjugates for gene delivery,” Journal of Medicinal Chemistry, vol. 45, no. 9, pp. 1817–1824, 2002. View at Publisher · View at Google Scholar · View at Scopus
  38. F. Thielbeer, K. Donaldson, and M. Bradley, “Zeta potential mediated reaction monitoring on nano and microparticles,” Bioconjugate Chemistry, vol. 22, no. 2, pp. 144–150, 2011. View at Publisher · View at Google Scholar
  39. Y. Malam, E. J. Lim, and A. M. Seifalian, “Current trends in the application of nanoparticles in drug delivery,” Current Medicinal Chemistry, vol. 18, no. 7, pp. 1067–1078, 2011. View at Publisher · View at Google Scholar
  40. G. Bonadonna, S. Monfardini, M. De Lena, F. Fossati-Bellani, and G. Beretta, “Phase I and preliminary phase II evaluation of adriamycin (NSC 123127),” Cancer Research, vol. 30, no. 10, pp. 2572–2582, 1970. View at Google Scholar · View at Scopus
  41. N. P. Niraula, S. H. Kim, J. K. Sohng, and E. S. Kim, “Biotechnological doxorubicin production: pathway and regulation engineering of strains for enhanced production,” Applied Microbiology and Biotechnology, vol. 87, no. 4, pp. 1187–1194, 2010. View at Publisher · View at Google Scholar · View at Scopus
  42. H. Meng, M. Liong, T. Xia et al., “Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and p-glycoprotein siRNA to overcome drug resistance in a cancer cell line,” ACS Nano, vol. 4, no. 8, pp. 4539–4550, 2010. View at Publisher · View at Google Scholar · View at Scopus