Effects of Atelocollagen Formulation Containing Oligonucleotide on Endothelial Permeability

Figure 1

Time-dependent reduction of TER after treatment with different types of oligonucleic acids in combination with atelocollagen. HMVEC cells were treated with 5 μM of oligonucleic acids with or without 0.1% atelocollagen. sODN: phosphorothioate oligodeoxynucleotide, oODN: phosphodiester oligodeoxynucleotide, dsRNA: small double stranded RNA. The sequences of the ODN are described in Table 1(a).