Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery

Table 3

Emulsifiers used for the production of lipid nanoparticles.

Emulsifiers/coemulsifiers	HLB	References
Lecithin	4–9	[92, 93]
Poloxamer 188	29	[94]
Poloxamer 407	21.5	[56, 95]
Tyloxapol	13	[96]
Polysorbate 20	16.7	[92]
Polysorbate 60	14.9	[97]
Polysorbate 80	15	[10, 11]
Sodium cholate	18	[98]
Sodium glycocholate	14.9	[99]
Taurodeoxycholic acid sodium	13-14	[100]
Butanol and Butyric acid	7–9	[101]
Cetylpyridinium chloride	~15	[102]
Sodium dodecyl sulphate	40	[103]
Sodium oleate	18	[99]
Polyvinyl alcohol	15–19	[104]
Cremophor EL	12–14	[105]