A Versatile Polymer Micelle Drug Delivery System for Encapsulation and In Vivo Stabilization of Hydrophobic Anticancer Drugs
Figure 5
Pharmacokinetics of daunorubicin-loaded micelles in rats. Sprague-Dawley rats were given a single intravenous administration of crosslinked daunorubicin micelle, uncrosslinked daunorubicin micelle, or free daunorubicin at a 10 mg/kg dose. Plasma was analyzed for daunorubicin concentration at various timepoints. The table depicts the area under curve (AUC) and values for each test article.