Research Article
A Mathematical Model for Thermosensitive Liposomal Delivery of Doxorubicin to Solid Tumour
Table 3
Parameters for doxorubicin (symbols are defined near the equations in which they first appear).
| | Parameter | Unit | Free doxorubicin | Bound doxorubicin | Reference |
| | m/s | 3.00 × 10−6 | 7.80 × 10−9 | [18, 26] | | | 2.56 | — | — | | m/s | 3.75 × 10−7 | 2.50 × 10−9 | [18, 26] | | m2/s | 3.40 × 10−10 | 8.89 × 10−12 | [18, 22, 27–31] | | m2/s | 1.58 × 10−10 | 4.17 × 10−12 | [18, 22, 27–31] | | MW | kg/mol | 0.544 | 69.0 | [12, 18] | | | 0.15 | 0.82 | [18, 32] | | s−1 | 0.833 | — | [22] | | s−1 | — | 0.278 | [22] | | kg/105 cells s | 4.67 × 10−15 | — | [22, 33] | | kg/m3 | 2.19 × 10−4 | — | [22, 33] | | kg/m3 | 1.37 × 10−12 | — | [22, 33] | | s−1 | 1.67 × 10−5 | — | [34] | | kg/105 cells | 5 × 10−13 | — | [34] | | kg | 8.56 × 10−5 | — | [1] | | m−3 |
74.6 |
74.6 | [22, 35] | | m−3 | 2.49 | 2.49 | [22, 35] | | m−3 | 0.552 | 0.552 | [22, 35] | | s−1 | 2.43 × 10−3 | 2.43 × 10−3 | [22, 35] | | s−1 | 2.83 × 10−4 | 2.83 × 10−4 | [22, 35] | | s−1 | 1.18 × 10−5 | 1.18 × 10−5 | [22, 35] | | s−1 | 3.0 × 10−6 | — | [36] | | s−1 | 3.0 × 10−16 | — | [36] | | s−1 | 1.48 × 10−5 | 0 | [35, 37–39] | | s−1 | 2.43 × 10−3 | 0 | [35, 37–39] |
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