Research Article

Design Optimization and In Vitro-In Vivo Evaluation of Orally Dissolving Strips of Clobazam

Table 6

Summary of results of regression analysis.

Coefficient

Disintegration time (sec)28.322221.56667−4.3333−0.07500−0.3331.66670.9242
Tensile strength (N/cm2)2.3911−0.565000.31167−0.01500−0.19160.128330.9124
% drug release81.70−5.16835.16830.100250−4.50161.998330.7620

, , , ,  , and represent regression coefficient of the independent variables (, ).