Research Article
Design Optimization and In Vitro-In Vivo Evaluation of Orally Dissolving Strips of Clobazam
Table 9
Intraday and interday precision accuracy of clobazam determination in rabbit plasma (
).
| Clobazam | Intraday | Interday | Accuracy | Concentration (ng/mL) | Area | %RSD | Area | %RSD | Quantity | Recovery | Spiked (ng/mL) |
| 10 | 4.324 | 0.5 | 5.085 | 1.1 | 10 | 10.57 | 20 | 6.049 | 0.9 | 6.158 | 1.1 | 20 | 18.09 | 25 | 7.655 | 6.2 | 8.798 | 0.3 | 25 | 25.55 | 40 | 12.06 | 3.0 | 12.24 | 0.8 | 40 | 39.36 | 50 | 15.23 | 2.4 | 16.32 | 1.4 | 50 | 49.58 | 75 | 22.88 | 0.8 | 20.59 | 0.4 | 75 | 74.76 | 100 | 30.98 | 0.7 | 30.95 | 1.6 | 100 | 100.69 |
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