Research Article
Preparation and Characterization of Liquisolid Compacts for Improved Dissolution of Telmisartan
Table 3
Evaluation parameters of LSC formulations (mean ± SD;
).
| | Formulation* | Friability (%) | Hardness (kg/cm2) | Disintegration tsime (min) | Angle of repose |
| | F1 | 0.54 ± 0.03 | 4 | 1.2 ± 0.08 | 29.64 ± 1.17 | | F2 | 0.68 ± 0.16 | 3 | 3.12 ± 0.13 | 34.64 ± 0.89 | | F3 | 0.63 ± 0.21 | 3 | 5.28 ± 0.05 | 45.23 ± 1.88 | | F4 | 0.59 ± 0.15 | 2 | 5.14 ± 0.04 | 45.03 ± 1.66 | | F5 | 0.66 ± 0.22 | 2 | 4.28 ± 0.11 | 35.06 ± 0.98 | | F6 | 0.64 ± 0.05 | 3 | 4.19 ± 0.09 | 39.24 ± 2.24 | | F1 after storage | 0.52 ± 0.15 | 4 | 1.4 ± 0.12 | 28.92 ± 2.12 |
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Refer Table 1 for formulation composition.
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