Development of Corn Starch-Neusilin UFL2 Conjugate as Tablet Superdisintegrant: Formulation and Evaluation of Fast Disintegrating Tablets

Table 1

Formulation table for preparing FDTs.

Code	Ingredients (mg)
	Domperidone	Native corn starch	Corn Starch-Neusilin UFL2 conjugate			Avicel 102	Magnesium stearate	Talc	TW*
			Physical mixture	Chemical mixture	Microwave mixture
F1	10	2.5	—	—	—	85.5	1	1	100
F2	10	5	—	—	—	83	1	1	100
F3	10	7.5	—	—	—	80.5	1	1	100
F4	10	10	—	—	—	78	1	1	100
F5	10	—	2.5	—	—	85.5	1	1	100
F6	10	—	5	—	—	83	1	1	100
F7	10	—	7.5	—	—	80.5	1	1	100
F8	10	—	10	—	—	78	1	1	100
F9	10	—	—	2.5	—	85.5	1	1	100
F10	10	—	—	5	—	83	1	1	100
F11	10	—	—	7.5	—	80.5	1	1	100
F12	10	—	—	10	—	78	1	1	100
F13	10	—	—	—	2.5	85.5	1	1	100
F14	10	—	—	—	5	83	1	1	100
F15	10	—	—	—	7.5	80.5	1	1	100
F16	10	—	—	—	10	78	1	1	100

TW*: total weight of tablet in mg.