Research Article

Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases

Scheme 1

Paclitaxel (PTX). (a) At left the locations of C2′OH and C7′OH are labeled; (b) at right, the C2′OH moiety has been coupled with a glutamic acid linker and the corresponding Phe-Phe-Arg tripeptide to give C2′-PTX-FFRck.