Hydroxypropyl-β-cyclodextrin: A Novel Transungual Permeation Enhancer for Development of Topical Drug Delivery System for Onychomycosis

Table 4

Effect of concentration of HP--CD on in vitro drug permeation (flux, ) of terbinafine hydrochloride from nail lacquer drug delivery formulations across nail clippings in 48 hr.

Concentration of HP--CD; (% w/v)	Formulation code	Flux (g/mL/cm^2) (mean ± S.D.) ()
0	L0	0.868 ± 0.06
6	L6	3.908 ± 0.05
7	L7	4.140 ± 0.11
8	L8	4.076 ± 0.15
9	L9	4.214 ± 0.05
10	L10	4.586 ± 0.08