Reassessing the Role of Intra-Arterial Drug Delivery for Glioblastoma Multiforme Treatment

Table 2

Recent clinical trials employing IA chemotherapy for CNS tumors.

Trial	Drugs	Tumor type
NCT01811498	Bevacizumab	GBM
NCT01238237	Cetuximab	GBM, anaplastic astrocytoma
NCT01180816	Temozolomide	GBM, anaplastic astrocytoma
NCT01269853	Bevacizumab	GBM, anaplastic astrocytoma
NCT00075387	Carboplatin-based chemotherapy	High grade glioma
NCT01083966	Bevacizumab	Vestibular schwannoma
NCT00253721	Melphalan	Brain and CNS tumors, lymphoma, and metastatic cancer
NCT01386710	Bevacizumab, Carboplatin	GBM, anaplastic astrocytoma
NCT00983398	Melphalan, Carboplatin, Sodium Thiosulfate, Filgrastim, and Pegfilgrastim	CNS embryonal tumors and germ cell tumors
NCT02285959	Bevacizumab	GBM
NCT01884740	Erbitux, Bevacizumab	GBM and other tumors