Research Article

Characterization and Compatibility Studies of Different Rate Retardant Polymer Loaded Microspheres by Solvent Evaporation Technique: In Vitro-In Vivo Study of Vildagliptin as a Model Drug

Table 1

Formulation of Vildagliptin microspheres prepared by emulsion solvent evaporation technique.

Formulation codePolymers (mg)
D : EURS100 : ECD : EURL100 : ECD : EURS100 : MK100MD : EURL100 : MK100M

VF11 : 1 : 1
VF21 : 1 : 2
VF31 : 1 : 3
VF41 : 1 : 1
VF51 : 1 : 2
VF61 : 1 : 3
VF101 : 1 : 1
VF111 : 1 : 2
VF121 : 1 : 3
VF131 : 1 : 1
VF141 : 1 : 2
VF151 : 1 : 3

D = drug, EC = Ethyl cellulose, EU = Eudragit, and M = Methocel.