Research Article

Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate, Cetirizine Hydrochloride in Combined Pharmaceutical Dosage Form: A New Era in Novel Drug Delivery for Pediatrics and Geriatrics

Table 7

Evaluation parameters for Salbutamol Sulphate, Cetirizine Hydrochloride FDT.

Serial
number
Evaluation parametersResults

1Weight variation (IP)Passed
2Thickness (mm) ± S.D3.63 ± 0.06
3Hardness (Kg/cm2) ± S.D1.8 ± 0.29
4Friability (%)0.3
5Disintegration time (sec) ± S.D45 ± 2.34
6Wetting time (sec) ± S.D28 ± 1.53
7Drug content uniformity (mg) ± S.DSAL-100.8 ± 3.36,
CET-104.7 ± 1.97

Average of three determinations.
Average of six determinations.