Dosing-Time Dependent Effects of Sodium Nitroprusside on Cerebral, Renal, and Hepatic Catalase Activity in Mice

Figure 2

Time course of CAT activity in the kidney of mice treated by i.p. route with SNP (2.5 mg/kg) or NaCl (0.9%). (a) Mice were treated with SNP or NaCl at 1 HALO. (b) Mice were treated with SNP or NaCl at 13 HALO. Data are expressed as mean ± SEM values from six different experiments in quadruplicate. The black bar corresponds to the dark period. Unpaired Student’s t-test revealed statistically significance: . Two-way ANOVA: time of sampling ((a) ; ; (b) ; ); treatment ((a) NS; (b) NS); time-treatment interaction ((a) ; ; (b) ; ).

(a)

(b)